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Key Product Details
| Description: | A3 selective agonist |
| Alternative Names: | CF 101, Piclidenoson |
| Chemical Name: | 1-Deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-N-methyl-β-D-ribofuranuronamide |
| Purity: | ≥97% (HPLC) |
| Molecular Weight: | 510.29 |
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Citations (12)
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Citations are publications that use Bio-Techne products. Selected citations for IB-MECA include:
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Ledderose et al.
(2016)
Adenosine arrests breast cancer cell motility by A3 receptor stimulation.
Purinergic Signalling.
2016;
PMID: 27577957 -
Ford et al.
(2015)
Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain.
J.Neurosci..
35:6057
PMID: 25878279 -
Eusemann et al.
(2015)
Adenosine Receptors Differentially Regulate the Expression of Regulators of G-Protein Signalling (RGS) 2, 3 and 4 in Astrocyte-Like Cells.
PLoS One.
10:e0134934
PMID: 26263491 -
Janes et al.
(2014)
A3 adenosine receptor agonist prevents the development of PacT.-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways.
Pain.
155:2560
PMID: 25242567 -
He et al.
(2013)
Adenosine regulates bone metabolism via A1, A2A, and A2B receptors in bone marrow cells from normal humans and patients with multiple myeloma.
FASEB J.
27:3446
PMID: 23682121 -
Kozma et al.
(2013)
Characterization by flow cytometry of fluorescent, selective agonist probes of the A(3) adenosine receptor.
Biochem Pharmacol.
85:1171
PMID: 23376019 -
Stoddart et al.
(2012)
Fragment screening at adenosine-A(3) receptors in living cells using a fluorescence-based binding assay.
Chem Biol.
19:1105
PMID: 22999879 -
Park et al.
(2012)
Proximal tubule sphingosine kinase-1 has a critical role in A1 adenosine receptor-mediated renal protection from ischemia.
Kidney Int.
82:878
PMID: 22695326 -
Keene et al.
(2010)
Multivalent dendrimeric and monomeric adenosine agonists attenuate cell death in HL-1 mouse cardiomyocytes expressing the A(3) receptor.
Biochem Pharmacol.
80:188
PMID: 20346920 -
Kornerup et al.
(2005)
Pharmacological characterisation of the adenosine receptor mediating increased ion transport in the mouse isolated trachea and the effect of allergen challenge.
Br J Pharmacol.
144:1011
PMID: 15685200 -
Feoktistov et al.
(2003)
Mast cell-mediated stimulation of angiogenesis: cooperative interaction between A2B and A3 adenosine receptors.
J Neurosci.
92:485
PMID: 12600879 -
Nieri et al.
(2001)
Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.
Br J Pharmacol.
134:745
PMID: 11606314
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