Honokiol

Tocris Bioscience, part of Bio-Techne | Catalog # 4590

Blocks NF-κB activation; also anti-inflammatory and antioxidant
Discontinued Product
4590 has been discontinued. View all NFkB/IkB Inhibitors products.

Key Product Details

Description

Blocks NF-κB activation; also anti-inflammatory and antioxidant

View all NFkB/IkB Inhibitors »

Product Description

Honokiol is an anti-inflammatory, antioxidant, antitumor and antiangiogenic agent. Blocks NF-κB activation by a variety of stimuli, including TNF and okadaic acid. Shown to scavenge superoxide and peroxyl radicals. Also inhibits a variety of inflammatory responses. Reverses cardiac hypertrophy in mice via SIRT3 activation.

Product Specifications

Molecular Weight

266.33

Formula

C18H18O2

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

5,3'-Diallyl-2,4'-dihydroxybiphenyl

CAS Number

35354-74-6

PubChem ID

72303

InChI Key

FVYXIJYOAGAUQK-UHFFFAOYSA-N

SMILES

OC1=C(C2=CC(CC=C)=C(O)C=C2)C=C(CC=C)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 26.63 100
Ethanol 26.63 100

Preparing Stock Solutions for Honokiol

The following data is based on the product molecular weight 266.33

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.75 mL 18.77 mL 37.55 mL
5 mM 0.75 mL 3.75 mL 7.51 mL
10 mM 0.38 mL 1.88 mL 3.75 mL
50 mM 0.08 mL 0.38 mL 0.75 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Honokiol

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Honokiol

For research use only

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