Herbimycin A

Novus Biologicals, part of Bio-Techne | Catalog # NB110-81565

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NB110-81565
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Product Summary for Herbimycin A

Hsp90 inhibitor. Synthetic Herbimycin A. 98% pure. Yellow solid.

Product Specifications

Application Notes

Soluble in DMSO and ethanol (1 mg/mL).

Scientific Data Images for Herbimycin A

Product Image: Herbimycin A [NB110-81565] - Chemical structure of Herbimycin A (NB110-81565), a Herbimycin A. Molecular Formula: C30H42N2O9. Molecular Weight: 574.3 g/mol.

Formulation, Preparation, and Storage

Concentration

Please see the protocols for proper use of this product. If no protocol is available, contact technical services for assistance.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Herbimycin A

Herbimycin A, a benzoquinoid ansamycin antibiotic, irreversibly and selectively inhibits tyrosine kinases by reacting with thiol groups (1, 2). It is effective on Src, Yes, Fps, Ros, Abl and ErbB oncogene products (1-3) and inhibits thrombin-induced tyrosine phosphorylation of phospholipase C (4).
1. Uehara Y., and Fukazawa H. (1991) Methods Enzymol. 201: 370.
2. Fukazawa H., et al. (1991) Biochem. Pharmacol. 42: 1661.
3. Satoh T., et al. (1992) J.Biol.Chem. 267: 2537.
4. Weiss R., and Nuccitelli R. (1992) J.Biol.Chem. 267:5608.

Additional Herbimycin A Products

Product Documents for Herbimycin A

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Certificate of Analysis

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Product Specific Notices for Herbimycin A

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Support products are guaranteed for 6 months from date of receipt.

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