HEAT hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0535
Highly selective α1 antagonist
Key Product Details
Description
Highly selective α1 antagonist
Alternative Names
BE 2254
Product Description
HEAT hydrochloride is a very selective α1-adrenoceptor antagonist, precursor of the 3-[125I]-derivative.Product Specifications
Molecular Weight
331.84
Formula
C19H21NO2.HCl
Storage
Desiccate at -20°C
Purity
≥98% (HPLC)
Chemical Name
2-{[β-(4-Hydroxyphenyl)ethyl]aminomethyl}-1-tetralone hydrochloride
CAS Number
30007-39-7
PubChem ID
34771
InChI Key
VCZXZECZIRGUCZ-UHFFFAOYSA-N
SMILES
Cl.OC1=CC=C(CCNCC2CCC3=CC=CC=C3C2=O)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.18 | 100 |
Preparing Stock Solutions
for HEAT hydrochloride
The following data is based on the product molecular weight 331.84
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.01 mL | 15.07 mL | 30.14 mL |
| 5 mM | 0.60 mL | 3.01 mL | 6.03 mL |
| 10 mM | 0.30 mL | 1.51 mL | 3.01 mL |
| 50 mM | 0.06 mL | 0.30 mL | 0.60 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Williams Interaction of 2-[β-(4-hydroxyphenyl)ethylaminomethyl]tetralone (BE 2254: 'HEAT') with catecholamine receptors in rat brain membranes. J.Pharm.Pharmacol. 1978 PMID: 26778
- Baumgarten Mechanisms of pressor effect of 5,6-dihydroxytryptamine in pithed rats. Naunyn Schmiedebergs Arch.Pharmacol. 1972 PMID: 4404780
Product Specific Notices for HEAT hydrochloride
For research use only
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