Haloperidol hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 0931

Dopamine antagonist; displays some D2 selectivity
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Key Product Details

Description

Dopamine antagonist; displays some D2 selectivity

View all Non-selective Dopamine Receptor Antagonists »

Product Description

Haloperidol hydrochloride is a dopamine antagonist with selectivity for D2-like receptors (Ki values are 1.2, ~ 7, 2.3, ~ 80 and ~ 100 nM for D2, D3, D4, D1 and D5 receptors respectively). Subtype-selective NMDA antagonist. Identified as targeting human host proteins that interact with SARS-CoV-2.

Product Specifications

Molecular Weight

412.33

Formula

C21H23ClFNO2.HCl

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone hydrochloride

CAS Number

1511-16-6

PubChem ID

11495267

InChI Key

JMRYYMBDXNZQMH-UHFFFAOYSA-N

SMILES

Cl.OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C1=CC=C(Cl)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 10.31 25 with gentle warming

Preparing Stock Solutions for Haloperidol hydrochloride

The following data is based on the product molecular weight 412.33

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 9.70 mL 48.50 mL 97.01 mL
1.25 mM 1.94 mL 9.70 mL 19.40 mL
2.5 mM 0.97 mL 4.85 mL 9.70 mL
12.5 mM 0.19 mL 0.97 mL 1.94 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Haloperidol hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Haloperidol hydrochloride

For research use only

⚠ WARNING: This product can expose you to chemicals including Haloperidol, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov
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