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GYKI 52466 dihydrochloride

Tocris Bioscience a Bio-Techne Brand

GYKI 52466 dihydrochloride | CAS No. 2319722-40-0 | Selective non-competitive AMPA antagonist
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Key Product Details

Description: Selective non-competitive AMPA antagonist
Chemical Name: 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-benzenamine dihydrochloride
Purity: ≥98% (HPLC)
Molecular Weight: 366.24

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  • Effective inhibitor of AMPA receptor calcium influx in neurons
    Name: Karthik Krishnamurthy
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Cultured rat motor neurons
    Preincubated 40 micromolar of GYKI 52466 for 10 minutes. The image shows the peak fluorescence intensity of fura2-am up on AMPA stimulation. GYKI 52466 efficiently inhibits AMPA receptor-mediated calcium influx.
    GYKI 52466 dihydrochloride Serum 1454

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Product Documents for GYKI 52466 dihydrochloride

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