Selective inhibitor of PLK1 and PLK3
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Key Product Details
Description: | Selective inhibitor of PLK1 and PLK3 |
Chemical Name: | 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]-2-thiophenecarboxamide |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 477.46 |
Citations for GW 843682X (9)
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Citations are publications that use Bio-Techne products. Selected citations for GW 843682X include:
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O'Connor et al.
(2015)
Requirement for PLK1 kinase activity in the maintenance of a robust spindle assembly checkpoint.
Eukaryot Cell.
5:42624
PMID: 26685311 -
Hu et al.
(2015)
The Centriole Cartwheel Protein SAS-6 in Trypanosoma brucei Is Required for Probasal Body Biogenesis and Flagellum Assembly.
Cell Cycle.
14:898
PMID: 26116214 -
Barton et al.
(2014)
Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1.
J Cell Biol.
206:877
PMID: 25267294 -
Hu et al.
(2013)
Polo-like kinase 1 (PLK1) is involved in toll-like receptor (TLR)-mediated TNF-α production in monocytic THP-1 cells.
PLoS One.
8:e78832
PMID: 24205328 -
Waxman
(2011)
Characterization of kinases involved in the phosphorylation of aggregated α-synuclein.
J Neurosci Res.
89:231
PMID: 21162130 -
Manchado et al.
(2010)
Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55α,δ phosphatase.
Cancer Cell.
18:641
PMID: 21156286 -
Pal et al.
(2010)
Role of a novel coiled-coil domain-containing protein CCDC69 in regulating central spindle assembly.
J Biol Chem.
9:4117
PMID: 20962590 -
Colnaghi and Wheatley
(2010)
Liaisons between survivin and Plk1 during cell division and cell death.
Exp Cell Res.
285:22592
PMID: 20427271 -
Scutt et al.
(2009)
Discovery and exploitation of inhibitor-resistant aurora and polo kinase mutants for the analysis of mitotic networks.
J Biol Chem.
284:15880
PMID: 19359241
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