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GW 7647

Tocris Bioscience a Bio-Techne Brand

PPAR alpha Receptor Agonists Small Molecule
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Key Product Details

Description: Highly selective, potent PPARα agonist. Orally active
Chemical Name: 2-[[4-[2-[[(Cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methylpropanoic acid
Purity: ≥99% (HPLC)
Molecular Weight: 502.75

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Citations for GW 7647 (8)

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Customer Reviews for GW 7647 (1)

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  • PPAR alpha agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages.
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: J774 murine macrophages
    GW7647 is the most potent PPARalpha agonist that reduces LPS-induced iNOS expression and NO production in macrophages by enhancing iNOS protein degradation through the proteasome pathway. Concentration 3, 10 and 30 uM showed dose-dependent inhibition.

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Product Documents for GW 7647

Certificate of Analysis

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