Granisetron hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2903

5-HT3 antagonist
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Key Product Details

Description

5-HT3 antagonist

Alternative Names

BRL 43694

View all 5-HT3 Receptor Antagonists »

Product Description

Granisetron hydrochloride is a 5-HT3 receptor antagonist that possesses potent antiemetic activity.

Product Specifications

Molecular Weight

348.87

Formula

C18H24N4O.HCl

Storage

Desiccate at +4°C

Purity

≥98% (HPLC)

Chemical Name

1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride

CAS Number

107007-99-8

PubChem ID

65264

InChI Key

QYZRTBKYBJRGJB-UHFFFAOYSA-N

SMILES

O=C(C3=NN(C)C4=C3C=CC=C4)NC1CC(N2C)CCCC2C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 34.89 100
DMSO 3.49 10

Preparing Stock Solutions for Granisetron hydrochloride

The following data is based on the product molecular weight 348.87

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.87 mL 14.33 mL 28.66 mL
5 mM 0.57 mL 2.87 mL 5.73 mL
10 mM 0.29 mL 1.43 mL 2.87 mL
50 mM 0.06 mL 0.29 mL 0.57 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Granisetron hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Granisetron hydrochloride

For research use only

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