GGsTop

Tocris Bioscience, part of Bio-Techne | Catalog # 4452

Inhibitor of γ-glutamyl transpeptidase (GGT)
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Key Product Details

Description

Inhibitor of γ-glutamyl transpeptidase (GGT)

View all Other Transferase Inhibitors »

Product Description

GGsTop is a selective, irreversible γ-glutamyl transpeptidase (GGT) inhibitor; displays no inhibitory effects on glutamine amidotransferases or asparagine synthetase. Suppresses oxidative stress by inhibiting GGT activation. Prevents ischemia/reperfusion-induced acute kidney injury in rats in vivo.

Product Specifications

Molecular Weight

331.26

Formula

C13H18NO7P

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

3-[[(3-Amino-3-carboxypropyl)methoxyphosphinyl]oxy]benzeneacetic acid

CAS Number

926281-37-0

PubChem ID

23582776

InChI Key

NTFPDEDRMYYPAC-UHFFFAOYSA-N

SMILES

NC(C(O)=O)CCP(OC1=CC=CC(CC(O)=O)=C1)(OC)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 6.63 20
DMSO 16.56 50

Preparing Stock Solutions for GGsTop

The following data is based on the product molecular weight 331.26

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 6.04 mL 30.19 mL 60.38 mL
2.5 mM 1.21 mL 6.04 mL 12.08 mL
5 mM 0.60 mL 3.02 mL 6.04 mL
25 mM 0.12 mL 0.60 mL 1.21 mL

Calculators

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Reconstitution Calculator

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Product Documents for GGsTop

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for GGsTop

For research use only

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