Fluvoxamine maleate
Tocris Bioscience, part of Bio-Techne | Catalog # 1033
5-HT reuptake inhibitor
Product Description
Fluvoxamine maleate is a selective serotonin reuptake inhibitor; antidepressant. Binds to the human 5-HT transporter with a Ki of 1.6 nmol/l.Product Specifications
Molecular Weight
434.41
Formula
C15H21F3N2O2.C4H4O4
Storage
Desiccate at +4°C
Purity
≥99%
Chemical Name
(E)-5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone-O-(2-aminoethyl)oxime maleate
CAS Number
61718-82-9
PubChem ID
9560989
InChI Key
LFMYNZPAVPMEGP-PIDGMYBPSA-N
SMILES
OC(=O)\C=C/C(O)=O.COCCCC\C(C1=CC=C(C=C1)C(F)(F)F)=N/OCCN
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 4.34 | 10 |
Preparing Stock Solutions
for Fluvoxamine maleate
The following data is based on the product molecular weight 434.41
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.02 mL | 115.10 mL | 230.20 mL |
| 0.5 mM | 4.60 mL | 23.02 mL | 46.04 mL |
| 1 mM | 2.30 mL | 11.51 mL | 23.02 mL |
| 5 mM | 0.46 mL | 2.30 mL | 4.60 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Owens Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J.Pharmacol.Exp.Ther. 1997 PMID: 9400006
- Classen Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor. Br.J.Pharmacol. 1977 PMID: 302726
- Narita Interactions of selective serotonin reuptake inhibitors with subtypes of σ receptors in rat brain. Eur.J.Pharmacol. 1996 PMID: 8831113
- Benfield and Ward Fluvoxamine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness. Drugs 1986 PMID: 3096686
Product Specific Notices for Fluvoxamine maleate
For research use only
Loading...
Loading...