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Flupirtine maleate

Tocris Bioscience a Bio-Techne Brand

Non-selective/Other Potassium Channel Activators Small Molecule
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Key Product Details

Description: KV7 channel activator; also GABAA modulator and indirect NMDA antagonist
Alternative Names: D 9998
Chemical Name: N-[2-Amino-6-[[4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester maleate
Purity: ≥98% (HPLC)
Molecular Weight: 420.4

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Citations for Flupirtine maleate (2)

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Customer Reviews for Flupirtine maleate (2)

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  • Flupirtine maleate effect on liver injury
    Name: Sadequl Islam
    Species: Mouse
    Assay Type: In Vivo
    Used flupirtine to understand how its analgesic effects correlate to its liver injury history. Flupirtine maleate dissloved easily in DMSO and worked nicely in experimental environment The product performed well under study conditions
    Flupirtine maleate Serum 2867
  • Flupirtine studied on HEK 293 cell line : Worked ideally on experiemental conditions
    Name: Farzana Islam
    Species: Human
    Cell Line/Tissue: HEK 293
    The Flupirtine maleate worked excellent in study conditions and I would go back to this one everytime I need it. Flupirtine is a non-opioid non-analgesic drug prescribed in some European countries to treat post surgery patients for pain relief. My study involved investigating whether Flupirtine shows BK channel opening properties. Flupirtine works on SK channel and thus it can be speculated that it also works on BK channel to affect neuron excitability. I have used 4 different concentrations of the Flupirtine drug(0.1,1,10 and 100 microgram) to test on HEK 293 cells.NS1619 was used as a standard BK channel opener to compare its channel opening properties.
    Dissolve in sterile DMSO under hood if sterile Flupirtine is required.
    Flupirtine maleate Serum 2867

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Product Documents for Flupirtine maleate

Certificate of Analysis

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