FCCP
Tocris Bioscience, part of Bio-Techne | Catalog # 0453
Oxidative phosphorylation uncoupler
Key Product Details
Description
Oxidative phosphorylation uncoupler
Product Description
FCCP is a very potent uncoupler of oxidative phosphorylation in mitochondria.Product Specifications
Molecular Weight
254.17
Formula
C10H5F3N4O
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone
CAS Number
370-86-5
PubChem ID
3330
InChI Key
BMZRVOVNUMQTIN-UHFFFAOYSA-N
SMILES
N#CC(C#N)=NNC1=CC=C(OC(F)(F)F)C=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 25.42 | 100 |
Preparing Stock Solutions
for FCCP
The following data is based on the product molecular weight 254.17
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.93 mL | 19.67 mL | 39.34 mL |
| 5 mM | 0.79 mL | 3.93 mL | 7.87 mL |
| 10 mM | 0.39 mL | 1.97 mL | 3.93 mL |
| 50 mM | 0.08 mL | 0.39 mL | 0.79 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Heytler and Pritchard A new class of uncoupling agents - carbonyl cyanide phenylhydrazones. Biochem.Biophys.Res.Commun. 1962 PMID: 13907155
- Connop Novel effects of FCCP [carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone] on amyloid precursor protein processing. J.Neurochem. 1999 PMID: 10098849
Product Specific Notices for FCCP
For research use only
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