Epoprostenol

Name: Epoprostenol
Brand: Tocris Bioscience
SKU: 2989

Tocris Bioscience, part of Bio-Techne | Catalog # 2989

Citations (13)

COA / SDS

Endogenous IP receptor agonist

Key Product Details

Description:	Endogenous IP receptor agonist
Alternative Names:	Prostaglandin I₂,Prostacyclin
Chemical Name:	(5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt
Purity:	≥98% (HPLC)
Molecular Weight:	374.45

View Full Technical Details for Epoprostenol

Technical Data
Citations

Biological Activity for Epoprostenol

Epoprostenol is an endogenous prostanoid that is a potent agonist at IP prostanoid receptors. Inhibits platelet aggregation and induces vasodilation.

Technical Data for Epoprostenol

M. Wt	374.45
Formula	C₂₀H₃₁NaO₅
Storage	Store at -80°C
Purity	≥98% (HPLC)
CAS Number	61849-14-7
PubChem ID	6364626
InChi Key	LMHIPJMTZHDKEW-XQYLJSSYSA-M
Smiles	[Na+].CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2O\C(C[C@H]12)=C/CCCC([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Epoprostenol

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	37.44	100

Preparing Stock Solutions for Epoprostenol

The following data is based on the product molecular weight 374.45.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.67 mL	13.35 mL	26.71 mL
5 mM	0.53 mL	2.67 mL	5.34 mL
10 mM	0.27 mL	1.34 mL	2.67 mL
50 mM	0.05 mL	0.27 mL	0.53 mL

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References for Epoprostenol

References are publications that support the biological activity of the product.

Oliva and Nicosia PGI₂-receptors and molecular mechanisms in platelets and vasculature: state of the art. Pharmacol.Res.Comm.
Kobzar Comparison of anti-aggregatory effects of PGI₂, PGI₃ and ilo. on human and rabbit platelets. Cell.Physiol.Biochem. 2001 PMID: 11684817