Ellipticine

Tocris Bioscience, part of Bio-Techne | Catalog # 3357

Antitumor and intercalating agent; inhibits DNA topoisomerase II
Discontinued Product
3357 has been discontinued. View all DNA Topoisomerase Inhibitors products.

Key Product Details

Description

Antitumor and intercalating agent; inhibits DNA topoisomerase II

View all DNA Topoisomerase Inhibitors »

Product Description

Ellipticine is a naturally occurring plant alkaloid with antitumor activity. DNA intercalating agent; blocks DNA topoisomerase II activity. Prevents p53 phosphorylation in lung cancer cells.

Product Specifications

Molecular Weight

246.31

Formula

C17H14N2

Storage

Store at +4°C

Purity

≥97% (HPLC)

Chemical Name

5,11-Dimethyl-6H-pyrido[4,3-b]carbazole

CAS Number

519-23-3

PubChem ID

3213

InChI Key

CTSPAMFJBXKSOY-UHFFFAOYSA-N

SMILES

CC1=C4C(C=CN=C4)=C(C)C3=C1C2=C(N3)C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 12.32 50

Preparing Stock Solutions for Ellipticine

The following data is based on the product molecular weight 246.31

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 8.12 mL 40.60 mL 81.20 mL
2.5 mM 1.62 mL 8.12 mL 16.24 mL
5 mM 0.81 mL 4.06 mL 8.12 mL
25 mM 0.16 mL 0.81 mL 1.62 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Ellipticine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ellipticine

For research use only

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