Key Product Details
Description: | TRPV agonist |
Chemical Name: | (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide |
Purity: | ≥98% (HPLC) |
Molecular Weight: | 305.42 |
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Citations for (E)-Capsaicin (38)
Citations are publications that use Bio-Techne products. Selected citations for (E)-Capsaicin include:
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Diniz et al.
(2019)
Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors.
PeerJ.
7:e6493
PMID: 30809460 -
Balleza-Tapia et al.
(2018)
TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro.
Elife.
7
PMID: 30417826 -
Yissachar et al.
(2017)
An Intestinal Organ Culture System Uncovers a Role for the Nervous System in Microbe-Immune Crosstalk.
Cell.
168:1135
PMID: 28262351 -
Chen et al.
(2016)
Spatial Distribution of the Cannabinoid Type 1 and Capsaicin Receptors May Contribute to the Complexity of Their Crosstalk.
Sci Rep.
6:33307
PMID: 27653550 -
Ma et al.
(2015)
Experimental evidence for alleviating nociceptive hypersensitivity by single application of capsaicin.
Mol Pain.
11:22
PMID: 25896608 -
Shi et al.
(2015)
Alterations in serotonin, transient receptor potential channels and protease-activated receptors in rats with irritable bowel syndrome attenuated by Shugan decoction.
Front Cell Neurosci.
21:4852
PMID: 25944998 -
Zakharov et al.
(2015)
Hunting for origins of migraine pain: cluster analysis of spontaneous and capsaicin-induced firing in meningeal trigeminal nerve fibers.
J Transl Med.
9:287
PMID: 26283923 -
Wang et al.
(2015)
Mother root of Aconitum carmichaelii Debeaux exerts antinociceptive effect in Complet Freund's Adjuvant-induced mice: roles of dynorpin/κ-opioid system and transient receptor potential vanilloid type-1 ion channel.
PLoS One.
13:284
PMID: 26320055 -
Chen et al.
(2015)
Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner.
Nature.
10:e0145556
PMID: 26700862 -
Stanley et al.
(2015)
Cannabidiol causes endothelium-dependent vasorelaxation of human mesenteric arteries via CB1 activation.
Neuropsychopharmacology.
107:568
PMID: 26092099 -
Rossi et al.
(2014)
Interleukin-1β causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53.
Mol Neurodegener.
9:56
PMID: 25495224 -
Wang et al.
(2014)
Innervation of enteric mast cells by primary spinal afferents in guinea pig and human small intestine.
Am J Physiol Gastrointest Liver Physiol.
307:G719
PMID: 25147231 -
Nguyen et al.
(2014)
Transient receptor potential vanilloid type 1 channel may modulate opioid reward.
Neuropsychopharmacology.
39:2414
PMID: 24732880 -
Chen et al.
(2014)
Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal pain.
Mol Pain.
20:1298
PMID: 24574803 -
Hartley et al.
(2013)
Development and experimental application of an HPLC procedure for the determination of capsaicin and dihydrocapsaicin in serum samples from human subjects.
Indian J Clin Biochem.
28:329
PMID: 24426233 -
Nesuashvili et al.
(2013)
Sensory nerve terminal mitochondrial dysfunction activates airway sensory nerves via transient receptor potential (TRP) channels.
Mol Pharmacol.
83:1007
PMID: 23444014 -
Shabir et al.
(2013)
Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium.
Diabetes.
305:F396
PMID: 23720349 -
Chiu et al.
(2013)
Bacteria activate sensory neurons that modulate pain and inflammation.
World J Gastroenterol.
501:52
PMID: 23965627 -
Fairless et al.
(2013)
Membrane potential measurements of isolated neurons using a voltage-sensitive dye.
PLoS One.
8:e58260
PMID: 23516458 -
Gao et al.
(2012)
Transient receptor potential vanilloid type 1-dependent regulation of liver-related neurons in the paraventricular nucleus of the hypothalamus diminished in the type 1 diabetic mouse.
Acta Neurochir Suppl.
61:1381
PMID: 22492526 -
Nash et al.
(2012)
7-tert-Butyl-6-(4-chloro-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one, a classic polymodal inhibitor of transient receptor potential vanilloid type 1 with a reduced liability for hyperthermia, is analgesic and ameliorates visceral hypersen
J Pharmacol Exp Ther.
342:389
PMID: 22566669 -
Khatibi et al.
(2011)
Capsaicin pre-treatment provides neurovascular protection against neonatal hypoxic-ischemic brain injury in rats.
Mol Pain.
111:225
PMID: 21725760 -
Zsombok et al.
(2011)
Functional plasticity of central TRPV1 receptors in brainstem dorsal vagal complex circuits of streptozotocin-treated hyperglycemic mice.
Exp Neurol.
31:14024
PMID: 21957263 -
Martínez-García et al.
(2011)
Increase of capsaicin-induced trigeminal Fos-like immunoreactivity by 5-HT(7) receptors.
Cardiovasc Res.
51:1511
PMID: 22082421 -
Buznikov et al.
(2010)
A putative 'pre-nervous' endocannabinoid system in early echinoderm development.
Dev Neurosci.
32:1
PMID: 19907129 -
Westlund et al.
(2010)
Impact of central and peripheral TRPV1 and ROS levels on proinflammatory mediators and nociceptive behavior.
Proc Natl Acad Sci U S A.
6:46
PMID: 20691059 -
Bhaskaran and Smith
(2010)
Effects of TRPV1 activation on synaptic excitation in the dentate gyrus of a mouse model of temporal lobe epilepsy.
World J Gastroenterol.
223:529
PMID: 20144892 -
Cobellis et al.
(2010)
A gradient of 2-arachidonoylglycerol regulates mouse epididymal sperm cell start-up.
Biol Reprod.
82:451
PMID: 19812302 -
Gibson et al.
(2008)
TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons.
Neuron.
57:746
PMID: 18341994 -
Benninger et al.
(2008)
Control of excitatory synaptic transmission by capsaicin is unaltered in TRPV1 vanilloid receptor knockout mice.
Br J Pharmacol.
52:89
PMID: 17651868 -
Pitcher et al.
(2007)
Spinal NKCC1 blockade inhibits TRPV1-dependent referred allodynia.
J Pharmacol Exp Ther.
3:17
PMID: 17603899 -
Bautista et al.
(2005)
Pungent products from garlic activate the sensory ion channel TRPA1.
Br J Pharmacol.
102:12248
PMID: 16103371 -
Ahern et al.
(2005)
Extracellular cations sensitize and gate capsaicin receptor TRPV1 modulating pain signaling.
J Neurosci.
25:5109
PMID: 15917451 -
Bang et al.
(2004)
Neurokinin-1 receptor antagonists protect mice from CD95- and tumor necrosis factor-α-mediated apoptotic liver damage.
J Neurosci.
308:1174
PMID: 14617692 -
Melis et al.
(2004)
Endocannabinoids mediate presynaptic inhibition of glutamatergic transmission in rat ventral tegmental area DA neurons through activation of CB1 receptors.
J Neurosci.
24:53
PMID: 14715937 -
Smart et al.
(2002)
'Entourage' effects of N-acyl ethanolamines at human vanilloid receptors. Comparison of effects upon anandamide-induced vanilloid receptor activation and upon anandamide metabolism.
Headache.
136:452
PMID: 12023948 -
Craib et al.
(2001)
A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus.
Neurochem Int.
134:42581
PMID: 11522594 -
Izzo et al.
(2001)
Effect of vanilloid drugs on gastrointestinal transit in mice.
Br J Pharmacol.
132:1411
PMID: 11264233
There are no citations that match your criteria.