(E)-Capsaicin

Tocris Bioscience, part of Bio-Techne | Catalog # 0462

TRPV agonist
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Key Product Details

Description

TRPV agonist

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Product Description

(E)-Capsaicin is a prototypic vanilloid receptor agonist (pEC50 values are 7.97 and 7.10 at rat and human VR1 receptors respectively). Excites a subset of primary afferent sensory neurons, with subsequent antinociceptive and anti-inflammatory effects. Reversibly inhibits aggregation of platelets.

Product Specifications

Molecular Weight

305.42

Formula

C18H27NO3

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide

CAS Number

404-86-4

PubChem ID

1548943

InChI Key

YKPUWZUDDOIDPM-SOFGYWHQSA-N

SMILES

COC1=C(O)C=CC(CNC(=O)CCCC\C=C\C(C)C)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 15.27 50
Ethanol 15.27 50

Preparing Stock Solutions for (E)-Capsaicin

The following data is based on the product molecular weight 305.42

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 6.55 mL 32.74 mL 65.48 mL
2.5 mM 1.31 mL 6.55 mL 13.10 mL
5 mM 0.65 mL 3.27 mL 6.55 mL
25 mM 0.13 mL 0.65 mL 1.31 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for (E)-Capsaicin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for (E)-Capsaicin

For research use only

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