DSPE-PEG 2000 Azide
Tocris Bioscience, part of Bio-Techne | Catalog # 8837
PEGylated DSPE with azide reactive group
Key Product Details
Description
PEGylated DSPE with azide reactive group
Product Description
DSPE-PEG 2000 Azide is a functionalized phospholipid-polymer conjugate. It comprises a 1,2-distearoyl-sn-glycero-PE (DSPE) covalently coupled to a linear polyethylene glycol (Mr 2000) with an azide-terminated end for onward chemistry. It is commonly used to synthesize antibody-coupled liposomes and lipid nanoparticles. It has been used to make macrophage and EGFR antibody targeted LNPs using strain-promoted azide alkyne cycloaddition (SPAAC) click reaction.Product Specifications
Formula
(C2H4O)nC44H84N4O10P.NH4
Storage
Store at -20°C
Purity
≥90% (HPLC)
Chemical Name
1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-azido(polyethyleneglycol)-2000]
CAS Number
1938081-40-3
PubChem ID
168311704
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 10mg/ml in chloroform and to 10mg/ml in Ethanol |
Calculators
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Geisler EGFR-targeted ionizable lipid nanoparticles enhance in vivo mRNA delivery to the placenta. J.Control Release 2024 PMID: 38789090
- Zhao Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery. Proc.Natl.Acad.Sci.U.S.A. 2024 PMID: 38315853
Product Specific Notices for DSPE-PEG 2000 Azide
For research use only
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