DSP-4
Tocris Bioscience, part of Bio-Techne | Catalog # 2958
Adrenergic neurotoxin
Key Product Details
Description
Adrenergic neurotoxin
Product Description
DSP-4 is an adrenergic neurotoxin. Displays neurotoxic effects on both peripheral and central noradrenergic neurons.Product Specifications
Molecular Weight
313.06
Formula
C11H15BrClN.HCl
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride
CAS Number
40616-75-9
PubChem ID
38533
InChI Key
NDDRNRRNYOULND-UHFFFAOYSA-N
SMILES
BrC1=CC=CC=C1CN(CC)CCCl.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 31.31 | 100 | |
| Ethanol | 31.31 | 100 |
Preparing Stock Solutions
for DSP-4
The following data is based on the product molecular weight 313.06
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.19 mL | 15.97 mL | 31.94 mL |
| 5 mM | 0.64 mL | 3.19 mL | 6.39 mL |
| 10 mM | 0.32 mL | 1.60 mL | 3.19 mL |
| 50 mM | 0.06 mL | 0.32 mL | 0.64 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Kawamura Short and long term analysis of heart rate variations in spontaneous hypertensive rats: effect of DSP-4 administration. Biomed.Pharmacother. 2005 PMID: 16275495
- Haidkind Denervation of the locus coeruleus projections by treatment with the selective neurotoxin DSP-4 [N(2-chloroethyl)-N-ethyl-2-bromobenzylamine] reduces DA release potential in the nucleus accumbens shell in conscious rats. Neurosci.Letts.
- Jaim-Etcheverry and Zieher DSP-4: a novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats. Brain Res. 1980 PMID: 7370771
Product Specific Notices for DSP-4
For research use only
Loading...
Loading...