Key Product Details
Description: | Positive allosteric modulator of GABAA receptors; displays subunit selectivity |
Chemical Name: | 4-Chloro-N-[2-(2-thienyl)imidazo[1,2-a]pyridin-3-yl]benzamide |
Purity: | ≥97% (HPLC) |
Molecular Weight: | 353.83 |
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Citations for DS2 (8)
Citations are publications that use Bio-Techne products. Selected citations for DS2 include:
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Olander et al.
(2018)
Delineation of the functional properties and the mechanism of action of AA29504, an allosteric agonist and positive allosteric modulator of GABAA receptors.
Biochem Pharmacol.
150:305
PMID: 29454619 -
Patel et al.
(2016)
Context-Dependent Modulation of GABAAR-Mediated Tonic Currents.
J Neurosci.
36:607
PMID: 26758848 -
Tong et al.
(2015)
Ectopic Expression of α6 and δ GABAA Receptor Subunits in Hilar Somatostatin Neurons Increases Tonic Inhibition and Alters Network Activity in the Dentate Gyrus.
J Neurosci.
35:16142
PMID: 26658866 -
Hammer et al.
(2015)
Functional characterization of the 1,5-benzodiazepine clo. and its major active metabolite N-desmethylclobazam at human GABA(A) receptors expressed in Xenopus laevis oocytes.
PLoS One.
10:e0120239
PMID: 25798598 -
Mirheydari et al.
(2014)
Unexpected Properties of δ-Containing GABAA Receptors in Response to Ligands Interacting with the α+ β- Site.
Neurochem Res.
39:1057
PMID: 24072672 -
Kerti-Szigeti et al.
(2014)
Synaptic GABAA receptor clustering without the γ2 subunit.
Nat Methods.
34:10219
PMID: 25080584 -
Mennerick et al.
(2014)
Phosphatidylinositol 4,5-bisphosphate depletion fails to affect neurosteroid modulation of GABAA receptor function.
Psychopharmacology (Berl).
231:3493
PMID: 24553581 -
Shu et al.
(2012)
Characteristics of concatemeric GABA(A) receptors containing α4/δ subunits expressed in Xenopus oocytes.
Br J Pharmacol.
165:2228
PMID: 21950777
There are no citations that match your criteria.