Dobutamine hydrochloride

Name: Dobutamine hydrochloride
Brand: Tocris Bioscience
SKU: 0515
Price: 259 USD

Tocris Bioscience a Bio-Techne Brand

Catalog # 0515

Citations (3)

COA / SDS

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Key Product Details

Description:	α₁, β₁ and β₂ agonist
Chemical Name:	4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]aminoethyl-1,2-benzenediol hydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	337.85

View Full Technical Details for Dobutamine hydrochloride

Biological Activity for Dobutamine hydrochloride

Dobutamine hydrochloride is a β₁- and β₂-adrenoceptor agonist with some action at the α₁-adrenoceptor.

Compound Libraries for Dobutamine hydrochloride

Dobutamine hydrochloride is also offered as part of the Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.

Technical Data for Dobutamine hydrochloride

M. Wt	337.85
Formula	C₁₈H₂₃NO₃.HCl
Storage	Desiccate at RT
Purity	≥99% (HPLC)
CAS Number	49745-95-1
PubChem ID	65324
InChi Key	BQKADKWNRWCIJL-UHFFFAOYSA-N
Smiles	Cl.CC(CCC1=CC=C(O)C=C1)NCCC1=CC=C(O)C(O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Dobutamine hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	33.78	100

Preparing Stock Solutions for Dobutamine hydrochloride

The following data is based on the product molecular weight 337.85.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.96 mL	14.80 mL	29.60 mL
5 mM	0.59 mL	2.96 mL	5.92 mL
10 mM	0.30 mL	1.48 mL	2.96 mL
50 mM	0.06 mL	0.30 mL	0.59 mL

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References for Dobutamine hydrochloride

References are publications that support the biological activity of the product.

Deighton Characterization of the beta adrenoceptor subtype(s) mediating the positive inotropic effects of epinine, DA, dobutamine, denopamine and xamoterol in isolated human right atrium. J.Pharmacol.Exp.Ther. 1992 PMID: 1354251
Brown Dobutamine: positive inotropy by nonselective adrenoceptor agonism in isolated guinea pig and human myocardium. Naunyn Schmiedebergs Arch.Pharmacol. 1987 PMID: 3600817

Citations for Dobutamine hydrochloride (3)

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Citations are publications that use Bio-Techne products. Selected citations for Dobutamine hydrochloride include:

Li et al. (2017) Pericytes impair capillary blood flow and motor function after chronic spinal cord injury. Nat Med. 23:733
PMID: 28459438
Kaya et al. (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. Biol Reprod. 329:350
PMID: 19144685
Skeberdis et al. (1997) Pharmacological characterization of the receptors involved in the beta-adrenoceptor-mediated stimulation of the L-type Ca²⁺ current in frog ventricular myocytes. Br J Pharmacol. 121:1277
PMID: 9257904

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Product Documents for Dobutamine hydrochloride

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.