Dobutamine hydrochloride

Name: Dobutamine hydrochloride
Brand: Tocris Bioscience
SKU: 0515

Tocris Bioscience, part of Bio-Techne | Catalog # 0515

Citations (18)

COA / SDS

α1, β1 and β2 agonist

Key Product Details

Description:	α₁, β₁ and β₂ agonist
Chemical Name:	4-[2-[[3-(4-Hydroxyphenyl)-1-methylpropyl]aminoethyl-1,2-benzenediol hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	337.85

View Full Technical Details for Dobutamine hydrochloride

Technical Data
Citations

Biological Activity for Dobutamine hydrochloride

Dobutamine hydrochloride is a β₁- and β₂-adrenoceptor agonist with some action at the α₁-adrenoceptor.

Compound Libraries for Dobutamine hydrochloride

Dobutamine hydrochloride is also offered as part of the Tocriscreen FDA-Approved Drugs. Find out more about compound libraries available from Tocris.

Technical Data for Dobutamine hydrochloride

M. Wt	337.85
Formula	C₁₈H₂₃NO₃.HCl
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	49745-95-1
PubChem ID	65324
InChi Key	BQKADKWNRWCIJL-UHFFFAOYSA-N
Smiles	Cl.CC(CCC1=CC=C(O)C=C1)NCCC1=CC=C(O)C(O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Dobutamine hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	33.78	100

Preparing Stock Solutions for Dobutamine hydrochloride

The following data is based on the product molecular weight 337.85.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.96 mL	14.80 mL	29.60 mL
5 mM	0.59 mL	2.96 mL	5.92 mL
10 mM	0.30 mL	1.48 mL	2.96 mL
50 mM	0.06 mL	0.30 mL	0.59 mL

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Reconstitution Calculator

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References for Dobutamine hydrochloride

References are publications that support the biological activity of the product.

Deighton Characterization of the beta adrenoceptor subtype(s) mediating the positive inotropic effects of epinine, DA, dobutamine, denopamine and xamoterol in isolated human right atrium. J.Pharmacol.Exp.Ther. 1992 PMID: 1354251
Brown Dobutamine: positive inotropy by nonselective adrenoceptor agonism in isolated guinea pig and human myocardium. Naunyn Schmiedebergs Arch.Pharmacol. 1987 PMID: 3600817