DLin-KC2-DMA

Name: DLin-KC2-DMA
Brand: Tocris Bioscience
SKU: 8895

Tocris Bioscience, part of Bio-Techne | Catalog # 8895

COA / SDS

Ionizable cationic lipid

Key Product Details

Description:	Ionizable cationic lipid
Chemical Name:	2-[2,2-Di-[(9Z,12Z)-octadeca-9,12-dienyl]-1,3-dioxolan-4-yl]-N,N-dimethylethanamine
Purity:	≥95% (HPLC)
Molecular Weight:	642.11

View Full Technical Details for DLin-KC2-DMA

Technical Data
Citations

Biological Activity for DLin-KC2-DMA

DLin-KC2-DMA is an ionizable cationic lipid (pKa = 6.7), used in the formulation of lipid nanoparticles (LNPs) encapsulating siRNA or plasmid DNA for non-toxic delivery into cells in vitro and in vivo.

For more information on LNPs and available components see our Lipid Nanoparticles page.

Technical Data for DLin-KC2-DMA

M. Wt	642.11
Formula	C₄₃H₇₉NO₂
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	1190197-97-7
PubChem ID	44464860
InChi Key	LRFJOIPOPUJUMI-KWXKLSQISA-N
Smiles	C(CCCCCCC/C=C\C/C=C\CCCCC)C1(CCCCCCCC/C=C\C/C=C\CCCCC)OC(CCN(C)C)CO1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for DLin-KC2-DMA

Solubility

Soluble in ethanol (supplied pre-dissolved in anhydrous ethanol, 100mg/mL)

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References for DLin-KC2-DMA

References are publications that support the biological activity of the product.

Kulkarni Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA. Nanomedicine 2017 PMID: 28038954