DL-AP3
Tocris Bioscience, part of Bio-Techne | Catalog # 0125
Group I mGlu antagonist; also phosphoserine phosphatase inhibitor
Discontinued Product
0125 has been discontinued.
View all Group I mGluR Antagonists products.
Key Product Details
Description
Group I mGlu antagonist; also phosphoserine phosphatase inhibitor
Product Description
DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.Product Specifications
Molecular Weight
169.07
Formula
C3H8NO5P
Storage
Store at RT
Chemical Name
DL-2-Amino-3-phosphonopropionic acid
CAS Number
5652-28-8
PubChem ID
3857
InChI Key
LBTABPSJONFLPO-UHFFFAOYSA-N
SMILES
NC(CP(O)(O)=O)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1eq. NaOH | 16.91 | 100 |
Preparing Stock Solutions
for DL-AP3
The following data is based on the product molecular weight 169.07
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.91 mL | 29.57 mL | 59.15 mL |
| 5 mM | 1.18 mL | 5.91 mL | 11.83 mL |
| 10 mM | 0.59 mL | 2.96 mL | 5.91 mL |
| 50 mM | 0.12 mL | 0.59 mL | 1.18 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Hawkinson The metabotropic glutamate receptor antagonist L-2-amino-3-phosphonopropionic acid inhibits phosphoserine phosphatase. Eur.J.Pharmacol. 1996 PMID: 8832224
- Saugstad L-2-Amino-3-phosphonopropionic acid completely antagonizes metabotropic glutamate receptors 1α and 5 in Xenopus oocytes. Eur.J.Pharmacol. 1995 PMID: 7621916
- Evans The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 1982 PMID: 7042024
Product Specific Notices for DL-AP3
For research use only
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