DL-AP3

Name: DL-AP3
Brand: Tocris Bioscience
SKU: 0125

Tocris Bioscience a Bio-Techne Brand

Catalog # 0125

Citations (1)

COA / SDS

Discontinued Product

0125 has been discontinued. View all Group I mGluR Antagonists products.

Key Product Details

Description:	Group I mGlu antagonist; also phosphoserine phosphatase inhibitor
Chemical Name:	DL-2-Amino-3-phosphonopropionic acid
Molecular Weight:	169.07

View Full Technical Details for DL-AP3

Biological Activity for DL-AP3

DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.

Technical Data for DL-AP3

M. Wt	169.07
Formula	C₃H₈NO₅P
Storage	Store at RT
CAS Number	5652-28-8
PubChem ID	3857
InChi Key	LBTABPSJONFLPO-UHFFFAOYSA-N
Smiles	NC(CP(O)(O)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for DL-AP3

References are publications that support the biological activity of the product.

Hawkinson The metabotropic glutamate receptor antagonist L-2-amino-3-phosphonopropionic acid inhibits phosphoserine phosphatase. Eur.J.Pharmacol. 1996 PMID: 8832224
Saugstad L-2-Amino-3-phosphonopropionic acid completely antagonizes metabotropic glutamate receptors 1α and 5 in Xenopus oocytes. Eur.J.Pharmacol. 1995 PMID: 7621916
Evans The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 1982 PMID: 7042024

Citations for DL-AP3 (1)

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Citations are publications that use Bio-Techne products. Selected citations for DL-AP3 include:

Vance et al. (2015) PAR1-activated astrocytes in the nucleus of the solitary tract stimulate adjacent neurons via NMDA receptors. J Neurosci. 35:776
PMID: 25589770

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Product Documents for DL-AP3

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.