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Dihydrokainic acid

Glutamate (EAAT) Transporter Inhibitors Small Molecule

Key Product Details

Description: EAAT2 (GLT-1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake
Chemical Name: (2S,3S,4R)-2-Carboxy-4-isopropyl-3-pyrrolidineacetic acid

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  • Works as expected.
    Name: Dipa Pati | 26th May 2020
    Species: Mouse
    Assay Type: Ex Vivo
    Cell Line/Tissue: Bed nucleus of the stria terminalis
    We performed ex-vivo slice physiology on Bed nucleus of the stria terminalis (BNST) slices. We bath applied DHK (300 micromolar) on a BNST neuron in the current-clamp mode. DHK depolarized the neuron and the drug effect washed out.
    Works as expected. Serum 0111

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