Dibutyryl-cAMP, sodium salt New
Tocris Bioscience, part of Bio-Techne | Catalog # TB1141-RMU
Dibutyryl-cAMP, sodium salt synthesized to Ancillary Material Grade
Key Product Details
Description
Dibutyryl-cAMP, sodium salt synthesized to Ancillary Material Grade
Alternative Names
Bucladesine sodium
Product Description
Dibutyryl-cAMP sodium salt is a cell-permeable analog of cAMP that activates cAMP-dependent protein kinases and is a phosphodiesterase inhibitor. Combined with other reagents, dibutyryl-cAMP promotes differentiation of neural stem/progenitor cells (NSPCs) and other cell lines (see our protocol below) and increases survival rates of NSPCs and differentiation into neurons in vivo. Promotes neurite outgrowth in cell cultures. Dibutyryl-cAMP has anti-inflammatory activity and is used to promote wound healing. Choline acetyltransferase and vesicular acetylcholine transporter mRNA are increased in cells treated with dibutyryl-cAMP.For more information about how Dibutyryl-cAMP, sodium salt may be used, see our protocol: Generating Midbrain Dopaminergic Neurons from hPSCs
This product is Bio-Techne's ancillary Material Grade version of Dibutyryl-cAMP sodium salt (Cat. No. 1141). Suitable for use in research and further manufacturing of cell therapies. Find out more about our Ancillary Material Grade product range.
Product Specifications
Molecular Weight
491.37
Formula
C18H23N5NaO8P
Storage
Store at -20°C (± 5°C)
Purity
≥98%
Chemical Name
N6,O2'-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt
CAS Number
16980-89-5
PubChem ID
23663967
InChI Key
KRBZRVBLIUDQNG-JBVYASIDSA-M
SMILES
[H][C@]([C@]1([H])[C@H]2OC(CCC)=O)(COP(O1)([O-])=O)O[C@H]2N3C=NC4=C3N=CN=C4NC(CCC)=O.[Na+]
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
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Product Specific Notices for Dibutyryl-cAMP, sodium salt
For research use only
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