DFMO

Tocris Bioscience, part of Bio-Techne | Catalog # 2761

Ornithine decarboxylase inhibitor
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Key Product Details

Description

Ornithine decarboxylase inhibitor

Alternative Names

Eflornithine

View all Decarboxylase Inhibitors »

Product Description

DFMO is an irreversible inhibitor of ornithine decarboxylase (ODC) that inhibits polyamine biosynthesis. Displays antiapoptotic, antiangiogenic and antiparasitic activity. Induces re-expression of aberrantly silenced tumor suppressor genes when used in combination with oligoamine analogs.

Product Specifications

Molecular Weight

218.63

Formula

C6H12F2N2O2.HCl

Storage

Desiccate at RT

Chemical Name

DL-2-(Difluoromethyl)-ornithine hydrochloride

CAS Number

68278-23-9

PubChem ID

57004

InChI Key

VKDGNNYJFSHYKD-UHFFFAOYSA-N

SMILES

NC(C(F)F)(C(O)=O)CCCN.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 16.4 75

Preparing Stock Solutions for DFMO

The following data is based on the product molecular weight 218.63

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 6.10 mL 30.49 mL 60.99 mL
3.75 mM 1.22 mL 6.10 mL 12.20 mL
7.5 mM 0.61 mL 3.05 mL 6.10 mL
37.5 mM 0.12 mL 0.61 mL 1.22 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product.

Product Documents for DFMO

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DFMO

For research use only

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