DBHDA

Name: DBHDA
Brand: Tocris Bioscience
SKU: 6175

Tocris Bioscience, part of Bio-Techne | Catalog # 6175

COA / SDS

Reagent for synthetic biology; converts cysteine to dehydroalanine

Key Product Details

Description:	Reagent for synthetic biology; converts cysteine to dehydroalanine
Chemical Name:	2,5-Dibromohexanediamide
Molecular Weight:	301.96

View Full Technical Details for DBHDA

Technical Data
Citations

Biological Activity for DBHDA

DBHDA is a reagent for synthetic biology; converts cysteine to dehydroalanine (Dha).

Technical Data for DBHDA

M. Wt	301.96
Formula	C₆H₁₀Br₂N₂O₂
Storage	Store at +4°C
CAS Number	99584-96-0
PubChem ID	277410
InChi Key	PLSXNAQEJOGNKQ-UHFFFAOYSA-N
Smiles	NC(C(CCC(C(N)=O)Br)Br)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for DBHDA

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	30.2	100

Preparing Stock Solutions for DBHDA

The following data is based on the product molecular weight 301.96.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.31 mL	16.56 mL	33.12 mL
5 mM	0.66 mL	3.31 mL	6.62 mL
10 mM	0.33 mL	1.66 mL	3.31 mL
50 mM	0.07 mL	0.33 mL	0.66 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

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References for DBHDA

References are publications that support the biological activity of the product.

Lercher Generation of a synthetic GlcNAcylated nucleosome reveals regulation of stability by H2A-Thr101 GlcNAcylation. Nat.Commun. 2015 PMID: 26305776
Wright Posttranslational mutagenesis: a chemical strategy for exploring protein side-chain diversity. Science 2016 PMID: 27708059
Mulder A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes. Nat.Chem.Biol. 2016 PMID: 27182664
Chalker Methods for converting cysteine to dehydroalanine on peptides and proteins. Chem. Sci.