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Dantrolene, sodium salt

Ryanodine Receptor Inhibitors Small Molecule
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Key Product Details

Description: Ca2+ release inhibitor
Chemical Name: 1-[[[5-(4-Nitrophenyl)-2-furanyl]methylene]amino]-2,4-imidazolinedione sodium salt
Purity: ≥98% (HPLC)
Molecular Weight: 336.23

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  • Dantrolene modulates synaptic function
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Hippocampus
    Dantrolene was used to test impact of Ca2+ efflux from internal stores on neurotransmitter vesicle release in living neurons. Dantrolene, being added to intracellular solution, suppressed release of synaptic vesicles. Figure: change of a neuron electrical capacitance in response to series of electrical stimuli. Increase of electrical capacitance reflects increased number of vesicles fusing with cell membrane.
    Dantrolene, sodium salt Serum 0507

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