D-Serine
Tocris Bioscience, part of Bio-Techne | Catalog # 0226
Potentiator of NMDA recepors; acts at glycine site
Key Product Details
Description
Potentiator of NMDA recepors; acts at glycine site
Product Description
D-Serine is a glycine agonist at the NMDA receptor.Product Specifications
Molecular Weight
105.09
Formula
C3H7NO3
Storage
Store at RT
CAS Number
312-84-5
PubChem ID
71077
InChI Key
MTCFGRXMJLQNBG-UWTATZPHSA-N
SMILES
N[C@@]([H])([C@](O)=O)CO
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 100 |
Preparing Stock Solutions
for D-Serine
The following data is based on the product molecular weight 105.09
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 9.52 mL | 47.58 mL | 95.16 mL |
| 5 mM | 1.90 mL | 9.52 mL | 19.03 mL |
| 10 mM | 0.95 mL | 4.76 mL | 9.52 mL |
| 50 mM | 0.19 mL | 0.95 mL | 1.90 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Lodge Non-competitive NMDA antagonists. The NMDA Receptor (2nd edition). Eds. G.L.Collingr
- Mothet D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proc.Natl.Acad.Sci.USA 2000 PMID: 10781100
- Schell D-Serine as a neuromodulator: regional and developmental localizations in rat brain glia resemble NMDA receptors. J. Neurosci. 1997 PMID: 9030620
Product Specific Notices for D-Serine
For research use only
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