D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt

Name: D- myo -Inositol 1,4,5-trisphosphate, hexapotassium salt
Brand: Tocris Bioscience
SKU: 1482

Catalog # 1482 | Tocris Bioscience a Bio-Techne Brand

Citations (1)

COA / SDS

Ca2+ mobilizing second messenger

Key Product Details

Description:	Ca²⁺ mobilizing second messenger
Molecular Weight:	648.64

View Full Technical Details for D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt

Technical Data
Citations (1) / Reviews

Biological Activity

D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt is an important second messenger involved in Ca²⁺ mobilization from intracellular stores (EC₅₀ = 0.1 μM). Formed from the enzymatic hydrolysis of phosphatidyl inositol-4,5-bisphosphate.

Technical Data

M. Wt	648.64
Formula	C₆H₉O₁₅P₃.K₆
Storage	Store at -20°C
CAS Number	103476-24-0
PubChem ID	16219525
InChi Key	DVOPWCOAGWTTEN-PPKFVSOLSA-H
Smiles	[K+].[K+].[K+].[K+].[K+].[K+].O[C@@H]1[C@H](O)[C@@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@@H](O)[C@@H]1OP([O-])([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References

References are publications that support the biological activity of the product.

Wilcox New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor. TiPS 1998 PMID: 9850611
Murphy Enantiomers of myo-inositol-1,3,4-trisphosphate and myo-inositol-1,4,6-trisphosphate: stereospecific recognition by cerebellar and platelet myo-inositol-1,4,5-trisphosphate receptors. Mol.Pharmacol. 1996 PMID: 8913354
Joseph myo-Inositol 1,4,5-trisphosphate. J.Biol.Chem. 1984 PMID: 6607924

Citations for D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt (1)

Showing 1 - 1 of 1 citation Showing All

Search Title:

Citations are publications that use Bio-Techne products. Selected citations for D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt include:

Li et al. (2016) Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated Ins secretion. Cell Death Dis. 7:e2275
PMID: 27336719

There are no citations that match your criteria.