[D-Lys3]-GHRP-6
Tocris Bioscience, part of Bio-Techne | Catalog # 1922
Ghrelin receptor antagonist
Product Description
[D-Lys3]-GHRP-6 is an antagonist at the ghrelin receptor (GHS-R1a) (IC50 = 0.9 μM). Also weakly binds to melanocortin receptors (Ki = 26-120 μM). Centrally active in vivo.Product Specifications
Molecular Weight
930.12
Formula
C49H63N13O6
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
136054-22-3
PubChem ID
5311279
InChI Key
MGSNWNLPMHXGDD-DFWOJPNQSA-N
SMILES
[H]N[C@@H](CC1=CNC=N1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 0.5mg/ml in water |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Schioth Characterization of the binding of MSH-B, HP-228, GHRP-6 and 153N-6 to the human melanocortin receptor subtypes. Neuropeptides 1997 PMID: 9574823
- Traebert Ghrelin acts on leptin-responsive neurones in the rat arcuate nucleus. J.Neuroendocrinol. 2002 PMID: 12121496
- Pinilla Role of ghrelin in the control of GH secretion in prepubertal rats: interactions with excitatory amino acids. Neuroendocrinology 2003 PMID: 12624529
Product Specific Notices for [D-Lys3]-GHRP-6
For research use only
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