CYM 9484

Name: CYM 9484
Brand: Tocris Bioscience
SKU: 4606

Tocris Bioscience, part of Bio-Techne | Catalog # 4606

Citations (1)

COA / SDS

Potent NPY Y2 receptor antagonist

Key Product Details

Description:	Potent NPY Y₂ receptor antagonist
Chemical Name:	N-[4-[(Dimethylamino)sulfonyl]phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide
Purity:	≥98% (HPLC)
Molecular Weight:	509.63

View Full Technical Details for CYM 9484

Technical Data
Citations

Biological Activity for CYM 9484

CYM 9484 is a potent neuropeptide Y (NPY) Y₂ receptor antagonist (IC₅₀ = 19 nM).

Licensing Information

Sold under license from The Scripps Research Institute

Technical Data for CYM 9484

M. Wt	509.63
Formula	C₂₇H₃₁N₃O₃S₂
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	1383478-94-1
PubChem ID	66561564
InChi Key	VAUKHARIAMDAGF-UHFFFAOYSA-N
Smiles	OC(C2=CC=CC=C2)(C3=CC=CC=C3)C1CCN(C(NC4=CC=C(S(=O)(N(C)C)=O)C=C4)=S)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CYM 9484

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	50.96	100

Preparing Stock Solutions for CYM 9484

The following data is based on the product molecular weight 509.63.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.96 mL	9.81 mL	19.62 mL
5 mM	0.39 mL	1.96 mL	3.92 mL
10 mM	0.20 mL	0.98 mL	1.96 mL
50 mM	0.04 mL	0.20 mL	0.39 mL

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References for CYM 9484

References are publications that support the biological activity of the product.

Mittapalli Synthesis and SAR of selective small molecule neuropeptide Y Y2 receptor antagonists. Bioorg.Med.Chem.Lett. 2012 PMID: 22607676