Cyclothiazide

Tocris Bioscience, part of Bio-Techne | Catalog # 0713

Positive allosteric modulator of AMPA receptors; inhibits AMPA desensitization
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Key Product Details

Description

Positive allosteric modulator of AMPA receptors; inhibits AMPA desensitization

View all AMPA Receptor Modulators »

Product Description

Cyclothiazide is a positive allosteric modulator of AMPA receptors that potently inhibits AMPA receptor desensitization. Selective for the flip variant of each of the four receptor subunits.

Product Specifications

Molecular Weight

389.87

Formula

C14H16ClN3O4S2

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1,1-dioxide

CAS Number

2259-96-3

PubChem ID

2910

InChI Key

BOCUKUHCLICSIY-UHFFFAOYSA-N

SMILES

NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C1CC2CC1C=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 38.99 100
Ethanol 9.75 25

Preparing Stock Solutions for Cyclothiazide

The following data is based on the product molecular weight 389.87

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.56 mL 12.82 mL 25.65 mL
5 mM 0.51 mL 2.56 mL 5.13 mL
10 mM 0.26 mL 1.28 mL 2.56 mL
50 mM 0.05 mL 0.26 mL 0.51 mL

Calculators

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Product Documents for Cyclothiazide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Cyclothiazide

For research use only

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