C3-binding peptide; inhibits complement activation
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Key Product Details
Description: | C3-binding peptide; inhibits complement activation |
Purity: | ≥95% (HPLC) |
Molecular Weight: | 1550.77 |
Citations for Compstatin (7)
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Citations are publications that use Bio-Techne products. Selected citations for Compstatin include:
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Sharma et al.
(2021)
Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model.
Nat Commun.
12:7293
PMID: 34911940 -
Larsen et al.
(2019)
Evasion of Classical Complement Pathway Activation on Plasmodium falciparum-Infected Erythrocytes Opsonized by PfEMP1-Specific IgG.
Front Immunol.
9:3088
PMID: 30666256 -
Koupenova et al.
(2019)
The role of platelets in mediating a response to human influenza infection.
Nat Commun.
10:1780
PMID: 30992428 -
Lee et al.
(2014)
Mesenchymal stem cells infected with Mycoplasma arginini secrete complement C3 to regulate immunoglobulin production in b lymphocytes.
Cell Death Dis.
5:e1192
PMID: 24763049 -
Magge et al.
(2013)
Inhibitors of C5 complement enhance vaccinia virus oncolysis.
Cancer Gene Ther.
20:342
PMID: 23661042 -
Sun et al.
(2012)
Is asthma related to choroidal neovascularization?
Pharmacol Res Perspect.
7:e35415
PMID: 22567103 -
Yang et al.
(2009)
Cardiovascular inflammation and lesion cell apoptosis: a novel connection via the IF.-inducible immunoproteasome.
Arterioscler Thromb Vasc Biol.
29:1213
PMID: 19443843
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Customer Reviews for Compstatin (1)
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Species: MouseAssay Type: In VitroCell Line/Tissue: CHO/APPwtWe wanted to investigate whether alpha -secretase like activity in human cord blood serum is mediated by complement C3b enzymatic activity. Compstatin (Cat. No. 2585) pre-incubated in different doses with whole as well as C3 depleted cord blood serum for 15 min at 37°C followed by treatment in CHO/APPwt cells with these premix complexes for 2 h.
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