Cirazoline hydrochloride

Name: Cirazoline hydrochloride
Brand: Tocris Bioscience
SKU: 0888

Tocris Bioscience, part of Bio-Techne | Catalog # 0888

Citations (17)

COA / SDS

Selective α1 agonist

Key Product Details

Description:	Selective α₁ agonist
Chemical Name:	2-(2-Cyclopropylphenoxymethyl)imidazoline hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	252.74

View Full Technical Details for Cirazoline hydrochloride

Technical Data
Citations

Biological Activity for Cirazoline hydrochloride

Cirazoline hydrochloride is a selective α₁ agonist.

Technical Data for Cirazoline hydrochloride

M. Wt	252.74
Formula	C₁₃H₁₆N₂O.HCl
Storage	Store at RT
Purity	≥98% (HPLC)
CAS Number	40600-13-3
PubChem ID	11957512
InChi Key	XFRXWLWUUDJHPB-UHFFFAOYSA-N
Smiles	Cl.C(OC1=C(C=CC=C1)C1CC1)C1=NCCN1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Cirazoline hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	25.27	100
	DMSO	25.27	100

Preparing Stock Solutions for Cirazoline hydrochloride

The following data is based on the product molecular weight 252.74.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.96 mL	19.78 mL	39.57 mL
5 mM	0.79 mL	3.96 mL	7.91 mL
10 mM	0.40 mL	1.98 mL	3.96 mL
50 mM	0.08 mL	0.40 mL	0.79 mL

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Reconstitution Calculator

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References for Cirazoline hydrochloride

References are publications that support the biological activity of the product.

Gellai and Ruffolo Renal effects of selective alpha-1 and alpha-2 adrenoreceptor agonists in conscious normotensive rats. J.Pharmacol.Exp.Ther. 1987 PMID: 2882013
Wikberg and Uklen Further characterisation of the guinea pig cerebral cortex idazoxan receptor: solubilization, distinction from the imidazole site, and demonstration of cirazoline as an idazoxan receptor-selective drug. J.Neurochem. 1990 PMID: 1972387
Le Rouzic Binding of [³H]cirazoline to an imidazoline site in rat brain and kidney membranes. Eur.J.Pharmacol. 1995 PMID: 7589165