Cirazoline hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0888
Selective α1 agonist
Key Product Details
Description
Selective α1 agonist
Product Description
Cirazoline hydrochloride is a selective α1 agonist.Product Specifications
Molecular Weight
252.74
Formula
C13H16N2O.HCl
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
2-(2-Cyclopropylphenoxymethyl)imidazoline hydrochloride
CAS Number
40600-13-3
PubChem ID
11957512
InChI Key
XFRXWLWUUDJHPB-UHFFFAOYSA-N
SMILES
Cl.C(OC1=C(C=CC=C1)C1CC1)C1=NCCN1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 25.27 | 100 | |
| DMSO | 25.27 | 100 |
Preparing Stock Solutions
for Cirazoline hydrochloride
The following data is based on the product molecular weight 252.74
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.96 mL | 19.78 mL | 39.57 mL |
| 5 mM | 0.79 mL | 3.96 mL | 7.91 mL |
| 10 mM | 0.40 mL | 1.98 mL | 3.96 mL |
| 50 mM | 0.08 mL | 0.40 mL | 0.79 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Gellai and Ruffolo Renal effects of selective alpha-1 and alpha-2 adrenoreceptor agonists in conscious normotensive rats. J.Pharmacol.Exp.Ther. 1987 PMID: 2882013
- Wikberg and Uklen Further characterisation of the guinea pig cerebral cortex idazoxan receptor: solubilization, distinction from the imidazole site, and demonstration of cirazoline as an idazoxan receptor-selective drug. J.Neurochem. 1990 PMID: 1972387
- Le Rouzic Binding of [3H]cirazoline to an imidazoline site in rat brain and kidney membranes. Eur.J.Pharmacol. 1995 PMID: 7589165
Product Specific Notices for Cirazoline hydrochloride
For research use only
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