CHC

Tocris Bioscience, part of Bio-Techne | Catalog # 5029

MCT inhibitor; decreases glycoloysis
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Key Product Details

Description

MCT inhibitor; decreases glycoloysis

View all Monocarboxylate Transporter Inhibitors »

Product Description

CHC is a monocarboxylic acid transport (MCT) inhibitor. Exhibits antitumoral and antiangiogenic activity in gliomas in vivo; decreases glycolytic metabolism, migration, and invasion in U251 cells. Enhances the effect of antitumor agent temozolomide (Cat No. 2706). Blocks lactate efflux from glioma cells and sensitizes cells to irradiation.

Product Specifications

Molecular Weight

189.17

Formula

C10H7NO3

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid

CAS Number

28166-41-8

PubChem ID

5328791

InChI Key

AFVLVVWMAFSXCK-VMPITWQZSA-N

SMILES

OC1=CC=C(/C=C(C#N)/C(O)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 18.92 100
Ethanol 3.78 20

Preparing Stock Solutions for CHC

The following data is based on the product molecular weight 189.17

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.29 mL 26.43 mL 52.86 mL
5 mM 1.06 mL 5.29 mL 10.57 mL
10 mM 0.53 mL 2.64 mL 5.29 mL
50 mM 0.11 mL 0.53 mL 1.06 mL

Calculators

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Reconstitution Calculator

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Product Documents for CHC

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CHC

For research use only

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