CGRP 8-37 (rat)

Name: CGRP 8-37 (rat)
Brand: Tocris Bioscience
SKU: 1169

Tocris Bioscience, part of Bio-Techne | Catalog # 1169

Citations (13)

COA / SDS

CGRP antagonist

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Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

CGRP antagonist

Alternative Names

Calcitonin Gene-Related Peptide 8-37 (rat)

View all Calcitonin and Related Receptor Antagonists »

Product Description

CGRP 8-37 (rat) is a peptide antagonist for CGRP₁ receptors.

Product Specifications

Molecular Weight

3127.50

Formula

C₁₃₈H₂₂₄N₄₂O₄₁

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

129121-73-9

PubChem ID

90479762

InChI Key

HZKKKBMPFPSSKZ-QZMRZBIOSA-N

SMILES

[H]N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Background References

References are publications that support the biological activity of the product.

Poyner Structural determinants for binding to CGRP receptors expressed by human SK-N-MC and Col 29 cells: studies with chimeric and other peptides. Br.J.Pharmacol. 1998 PMID: 9756381
Wisskirchen Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens. Br.J.Pharmacol. 1998 PMID: 9605575
Poyner Pharmacology of receptors for calcitonin gene-related peptide and amylin. TiPS 1995 PMID: 8578616