CGP 3466B maleate

Tocris Bioscience, part of Bio-Techne | Catalog # 2966

GAPDH inhibitor; neuroprotective
Catalog #
Availability
Size / Price
Qty
2966/10
2966/50
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Description

GAPDH inhibitor; neuroprotective

Alternative Names

TCH 346 maleate

View all Dehydrogenase Inhibitors »

Product Description

CGP 3466B maleate is an orally active glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor. Exhibits antiapoptotic activity via inhibition of GAPDH nuclear translocation and mitochondrial complex 1-dependent H2O2 release. CGP 3466B inhibits colon cancer proliferation in vitro and displays neuroprotective activity in vivo.

Product Specifications

Molecular Weight

391.42

Formula

C19H17NO.C4H4O4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-(Dibenz[b,f]oxepin-10-ylmethyl)-N-Methyl-N-(2-propynyl)amine maleate

CAS Number

200189-97-5

PubChem ID

9821821

InChI Key

SQAZQLMBEHYFJA-BTJKTKAUSA-N

SMILES

O=C(O)/C=C\C(O)=O.CN(CC#C)CC2=CC1=CC=CC=C1OC3=C2C=CC=C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 3.91 10
DMSO 39.14 100

Preparing Stock Solutions for CGP 3466B maleate

The following data is based on the product molecular weight 391.42

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.55 mL 12.77 mL 25.55 mL
5 mM 0.51 mL 2.55 mL 5.11 mL
10 mM 0.26 mL 1.28 mL 2.55 mL
50 mM 0.05 mL 0.26 mL 0.51 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

x
=
x

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Product Documents for CGP 3466B maleate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CGP 3466B maleate

For research use only

Privacy Policy
Cookie Policy
Site Map
© Copyright 2026 Bio-Techne. All Rights Reserved. All trademarks and registered trademarks are the property of Bio-Techne and its brands unless otherwise specified.