CD22L-N3 (BPC-Sia-LacNAc-N3)
Tocris Bioscience, part of Bio-Techne | Catalog # 8830
CD22 ligand with azide group for onward chemistry
Key Product Details
Description
CD22 ligand with azide group for onward chemistry
Product Description
CD22L-N3 (BPC-Sia-LacNAc-N3) is a functionalized CD22 receptor ligand for trogocytosis targeting chimera (TrogoTAC) research and development. CD22 targeted TrogoTACs are bispecific molecules capable of inducing protein transfer from the target cell to B cells, by redirecting trogocytosis. Comprises an azide functionalized CD22 ligand for conjugation.Product Specifications
Molecular Weight
922.89
Formula
C40H54N6O19
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(2R,4S,5R,6R)-6-((1R,2R)-3-([1,1'-Biphenyl]-4-carboxamido)-1,2-dihydroxypropyl)-5-acetamido-2-(((2R,3R,4S,5R,6S)-6-(((2R,3S,4R,5R,6R)-5-acetamido-6-(2-azidoethoxy)-4-hydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methoxy)-4-hydroxytetrahydro-2H-pyran-2-carboxylic acid
CAS Number
1019642-47-7
PubChem ID
101550018
InChI Key
UTCPJMHBEGWJPH-LPKWDFCZSA-N
SMILES
O(C[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@H](OCCN=[N+]=[N-])[C@H](NC(C)=O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O)[C@@]3(C(O)=O)O[C@@]([C@@H]([C@@H](CNC(=O)C4=CC=C(C=C4)C5=CC=CC=C5)O)O)([C@H](NC(C)=O)[C@@H](O)C3)[H]
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 92.29 | 100 | |
| DMSO | 92.29 | 100 |
Preparing Stock Solutions
for CD22L-N3 (BPC-Sia-LacNAc-N3)
The following data is based on the product molecular weight 922.89
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.08 mL | 5.42 mL | 10.84 mL |
| 5 mM | 0.22 mL | 1.08 mL | 2.17 mL |
| 10 mM | 0.11 mL | 0.54 mL | 1.08 mL |
| 50 mM | 0.02 mL | 0.11 mL | 0.22 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Till Trogocytosis targeting chimeras (TrogoTACs) for targeted protein transfer. ChemRxiv
Product Specific Notices for CD22L-N3 (BPC-Sia-LacNAc-N3)
For research use only
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