Cardamonin

Tocris Bioscience, part of Bio-Techne | Catalog # 2509

Inhibitor of NF-κB activation; anti-inflammatory
Discontinued Product
2509 has been discontinued. View all NFkB/IkB Inhibitors products.

Key Product Details

Description

Inhibitor of NF-κB activation; anti-inflammatory

View all NFkB/IkB Inhibitors »

Product Description

Cardamonin is a chalone analog that display anti-inflammatory activity. Inhibits NO and PGE2 production from LPS- and IFN-γ-induced RAW cells and inhibits TXB2 production via the COX-1 and COX-2 pathways. Inhibits NF-κB activation via inhibition of IκBα degradation and phosphorylation, IκB kinase activation and NF-κB nuclear translocation.

Product Specifications

Molecular Weight

270.28

Formula

C16H14O4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

(2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one

CAS Number

19309-14-9

PubChem ID

641785

InChI Key

NYSZJNUIVUBQMM-BQYQJAHWSA-N

SMILES

OC1=CC(O)=C(C(/C=C/C2=CC=CC=C2)=O)C(OC)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 27.03 100
Ethanol 5.41 20

Preparing Stock Solutions for Cardamonin

The following data is based on the product molecular weight 270.28

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.70 mL 18.50 mL 37.00 mL
5 mM 0.74 mL 3.70 mL 7.40 mL
10 mM 0.37 mL 1.85 mL 3.70 mL
50 mM 0.07 mL 0.37 mL 0.74 mL

Calculators

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Product Documents for Cardamonin

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Cardamonin

For research use only

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