Calmidazolium chloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2561

Calmodulin antagonist
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Key Product Details

Description

Calmodulin antagonist

Alternative Names

R 24571

View all Calcium Binding Protein Modulator Antagonists »

Product Description

Calmidazolium chloride is a calmodulin antagonist. Inhibits calmodulin-dependent phosphodiesterase and Ca2+-transporting ATPase with IC50 values of 0.15 and 0.35 μM respectively. Also causes elevation of intracellular calcium in HL-60 cells, independent of calmodulin inhibition.

Product Specifications

Molecular Weight

687.70

Formula

C31H23Cl7N2O

Storage

Store at +4°C

Purity

≥95% (HPLC)

Chemical Name

1-[Bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-(2,4-dichlorobenzyloxy)ethyl]-1H-imidazolium chloride

CAS Number

57265-65-3

PubChem ID

644274

InChI Key

YGEIMSMISRCBFF-UHFFFAOYSA-M

SMILES

[Cl-].ClC1=CC=C(C=C1)C(N1C=C[N+](CC(OCC2=CC=C(Cl)C=C2Cl)C2=CC=C(Cl)C=C2Cl)=C1)C1=CC=C(Cl)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 68.77 100
Ethanol 68.77 100

Preparing Stock Solutions for Calmidazolium chloride

The following data is based on the product molecular weight 687.70

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.45 mL 7.27 mL 14.54 mL
5 mM 0.29 mL 1.45 mL 2.91 mL
10 mM 0.15 mL 0.73 mL 1.45 mL
50 mM 0.03 mL 0.15 mL 0.29 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Calmidazolium chloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Calmidazolium chloride

For research use only

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