C-type natriuretic peptide (1-22) (human, rat, swine)

Tocris Bioscience, part of Bio-Techne | Catalog # 3520

Endogenous peptide agonist at NPR2
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Key Product Details

Description

Endogenous peptide agonist at NPR2

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Product Description

C-type natriuretic peptide (1-22) (human, rat, swine) is an endogenous peptide found in plasma and cerebrospinal fluid. Behaves as an agonist at natriuretic peptide receptor NPR2 (NPRB) and exhibits affinity for NPR3 (NPRC). Inhibits L-type calcium currents in myocytes and exhibits antiproliferative effects in cardiac fibroblasts in vitro. Regulates cartilage homeostasis, body fluid volume and exhibits vasodilatory activity in vivo.

Product Specifications

Molecular Weight

2197.61

Formula

C93H157N27O28S3

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

127869-51-6

PubChem ID

16179407

InChI Key

UHSBKBYWHCBDCJ-DYGWFTAGSA-N

SMILES

[H]NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC2=CC=CC=C2)NC1=O)[C@@H](C)CC)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product.

Product Documents for C-type natriuretic peptide (1-22) (human, rat, swine)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for C-type natriuretic peptide (1-22) (human, rat, swine)

For research use only

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