BRL 44408 maleate

Tocris Bioscience, part of Bio-Techne | Catalog # 1133

Selective α2A antagonist
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Key Product Details

Description

Selective α2A antagonist

View all Adrenergic alpha-2 Receptor Antagonists »

Product Description

BRL 44408 maleate is a selective α2A-adrenoceptor antagonist (Ki = 1.7 nM and 144.5 nM at α2A and α2B-adrenergic receptors respectively). Increases hippocampal noradrenalin release following systemic administration.

Licensing Information

Sold with the permission of GlaxoSmithKline

Product Specifications

Molecular Weight

331.37

Formula

C13H17N3.C4H4O4

Storage

Desiccate at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole maleate

CAS Number

681806-46-2

PubChem ID

10382026

InChI Key

DDIQGSUEJOOQQQ-BTJKTKAUSA-N

SMILES

OC(=O)\C=C/C(O)=O.CC1N(CC2=NCCN2)CC2=C1C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 33.14 100

Preparing Stock Solutions for BRL 44408 maleate

The following data is based on the product molecular weight 331.37

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.02 mL 15.09 mL 30.18 mL
5 mM 0.60 mL 3.02 mL 6.04 mL
10 mM 0.30 mL 1.51 mL 3.02 mL
50 mM 0.06 mL 0.30 mL 0.60 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for BRL 44408 maleate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BRL 44408 maleate

For research use only

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