BML 111

Tocris Bioscience, part of Bio-Techne | Catalog # 5488

COA / SDS

FPR2 (lipoxin A4 receptor) agonist

Key Product Details

Description:	FPR2 (lipoxin A₄ receptor) agonist
Chemical Name:	(5S,6R)-Methyl 5,6,7-trihydroxyheptanoate
Molecular Weight:	192.21

View Full Technical Details for BML 111

Technical Data
Citations

Biological Activity for BML 111

BML 111 is a FPR2 (lipoxin A₄ receptor) agonist. Suppresses tumor-related angiogenesis and reduces tumor growth in hepatoma H22 cell bearing mice. Also protects against hemorrhagic shock-induced acute lung injury in rats. Lipoxin A₄ analog.

Technical Data for BML 111

M. Wt	192.21
Formula	C₈H₁₆O₅
Storage	Store at -20°C
CAS Number	78606-80-1
PubChem ID	10899465
InChi Key	RNMFWAFZUNVQOR-NKWVEPMBSA-N
Smiles	OC[C@@H](O)[C@@H](O)CCCC(OC)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for BML 111

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	19.22	100
	DMSO	19.22	100

Preparing Stock Solutions for BML 111

The following data is based on the product molecular weight 192.21.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.20 mL	26.01 mL	52.03 mL
5 mM	1.04 mL	5.20 mL	10.41 mL
10 mM	0.52 mL	2.60 mL	5.20 mL
50 mM	0.10 mL	0.52 mL	1.04 mL

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Reconstitution Calculator

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References for BML 111

References are publications that support the biological activity of the product.

Gong BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats. Resuscitation. 2012 PMID: 22245750
Chen Lipoxin A₄ and its analogue suppress the tumor growth of transplanted H22 in mice: the role of antiangiogenesis. Mol.Cancer.Ther. 2010 PMID: 20682645