Biotin-geldanamycin

Novus Biologicals, part of Bio-Techne | Catalog # NB110-81560

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NB110-81560
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Product Summary for Biotin-geldanamycin

Hsp90 inhibitor. MW 560.6.

Product Specifications

Specificity

Biotin- geldanamycin Compound

Application Notes

Synthetic Geldanamycin-Biotin 98% pure. Purple solid. Soluble in DMSO.

Reactivity Notes

Not species specific.

Scientific Data Images for Biotin-geldanamycin

Product Image: Biotin-geldanamycin [NB110-81560] - Chemical structure of Geldanamycin- Biotin (NB110-81560), a Biotin-geldanamycin. Molecular Formula: C55H87N7O17S. Molecular Weight: 560.6 g/mol.

Formulation, Preparation, and Storage

Concentration

Please see the protocols for proper use of this product. If no protocol is available, contact technical services for assistance.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Biotin-geldanamycin

Geldanamycin is a benzoquinoid ansamycin produced by Streptomyces hygroscopicus. It binds specifically to heat shock protein HSP90 and downregulates target proteins including tyrosine kinases, steroid receptors, transcription factors and cell cycle regulatory kinases (1,2). It induces the inactivation, destabilization and eventual degradation of HIF-1

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Product Documents for Biotin-geldanamycin

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Certificate of Analysis

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Product Specific Notices for Biotin-geldanamycin

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Support products are guaranteed for 6 months from date of receipt.

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