Bifemelane hydrochloride

Name: Bifemelane hydrochloride
Brand: tocris
SKU: 0767

Catalog # 0767

Datasheet / COA / SDS

Order Information

Bio-Techne Corporation

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$35 to United States

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Key Product Details

Description:	Non-selective MAO inhibitor
Chemical Name:	4-(2-Benzylphenoxy)-N-methylbutylamine hydrochloride
Purity:	≥99% (HPLC)
Molecular Weight:	305.84

View Full Technical Details for Bifemelane hydrochloride

Biological Activity

Bifemelane hydrochloride is an antidepressant MAO inhibitor. Reverses catalepsy induced by tetrabenazine in mice and increases locomotor activity in MPTP-treated marmosets.

Compound Libraries

Bifemelane hydrochloride is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data

M. Wt	305.84
Formula	C₁₈H₂₃NO.HCl
Storage	Desiccate at RT
Purity	≥99% (HPLC)
CAS Number	62232-46-6
PubChem ID	43962
InChi Key	MEAHDXWXNNDSAK-UHFFFAOYSA-N
Smiles	Cl.CNCCCCOC1=CC=CC=C1CC1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	30.58	100
	DMSO	30.58	100

Preparing Stock Solutions

The following data is based on the product molecular weight 305.84.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.27 mL	16.35 mL	32.70 mL
5 mM	0.65 mL	3.27 mL	6.54 mL
10 mM	0.33 mL	1.63 mL	3.27 mL
50 mM	0.07 mL	0.33 mL	0.65 mL

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Reconstitution Calculator

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References

References are publications that support the biological activity of the product.

Naoi 4-(o-benzylphenoxy)-N-methylbutylamine (bifemelane) and other 4-(o-benzylphenoxy)-N-methylalkylamines as new inhibitors of type A and B monoamine oxidase. J.Neurochem. 1988 PMID: 3335842
Nomoto Effects of bifemelane on parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset. Neurosci.Lett. 1994 PMID: 7816348
Tobe Pharmacological evaluation of 2-(4-methylaminobutoxy)diphenylmethane hydrochloride (MCl-2016), a new psychotropic drug with antidepressant activity. Arzneimittelforschung 1981 PMID: 7197535