BIBR 1532

Tocris Bioscience, part of Bio-Techne | Catalog # 2981

Selective telomerase inhibitor
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Key Product Details

Description

Selective telomerase inhibitor

View all Telomerase Inhibitors »

Product Description

BIBR 1532 is a selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively). Causes telomere shortening in exponentially growing NCI-H460 lung carcinoma cells and eventual growth arrest.

Product Specifications

Molecular Weight

331.36

Formula

C21H17NO3

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl1-yl]amino]benzoic acid

CAS Number

321674-73-1

PubChem ID

9927531

InChI Key

PGFQXGLPJUCTOI-WYMLVPIESA-N

SMILES

C/C(C2=CC1=CC=CC=C1C=C2)=C\C(NC3=C(C(O)=O)C=CC=C3)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 33.14 100
Ethanol 8.28 25

Preparing Stock Solutions for BIBR 1532

The following data is based on the product molecular weight 331.36

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.02 mL 15.09 mL 30.18 mL
5 mM 0.60 mL 3.02 mL 6.04 mL
10 mM 0.30 mL 1.51 mL 3.02 mL
50 mM 0.06 mL 0.30 mL 0.60 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for BIBR 1532

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BIBR 1532

For research use only

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