BI 01383298
Tocris Bioscience, part of Bio-Techne | Catalog # 6518
Potent and selective SLC13A5 (Na+/citrate cotransporter) inhibitor
Key Product Details
Description
Potent and selective SLC13A5 (Na+/citrate cotransporter) inhibitor
Product Description
BI 01383298 is a potent and selective inhibitor of human SLC13A5 (Na+/citrate cotransporter; IC50 = 56 nM in HEK cells overexpressing hSLC13A5 and 24 nM in HepG2 cells with endogenous SLC13A5 expression). Displays >1000-fold selectivity over other family members.Licensing Information
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the BI01383298 probe summary on the SGC website.Product Specifications
Molecular Weight
445.34
Formula
C19H19Cl2FN2O3S
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
1-[(3,5-Dichlorophenyl)sulfonyl]-N-[(4-fluorophenyl)methyl]-4-piperidinecarboxamide
CAS Number
2227549-00-8
PubChem ID
134604213
InChI Key
VUOYAALVGSMUHC-UHFFFAOYSA-N
SMILES
FC1=CC=C(C=C1)CNC(C2CCN(S(=O)(C3=CC(Cl)=CC(Cl)=C3)=O)CC2)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 22.27 | 50 |
Preparing Stock Solutions
for BI 01383298
The following data is based on the product molecular weight 445.34
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 4.49 mL | 22.45 mL | 44.91 mL |
| 2.5 mM | 0.90 mL | 4.49 mL | 8.98 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.49 mL |
| 25 mM | 0.09 mL | 0.45 mL | 0.90 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Peters Flipping a citrate switch on liver cancer cells. J.Biol.Chem. 2017 PMID: 28821606
Product Specific Notices for BI 01383298
For research use only
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