BAY-u 3405

Tocris Bioscience, part of Bio-Techne | Catalog # 2732

Dual TP/DP2 (CRTH2) receptor antagonist
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Key Product Details

Description

Dual TP/DP2 (CRTH2) receptor antagonist

Alternative Names

Ramatroban

View all Prostanoid Receptor Antagonists »

Product Description

BAY-u 3405 is a potent dual antagonist of TP/DP2 (CRTH2) prostanoid receptors (Ki values are 4.3, 4.5 and > 10000 nM for hDP2, hTP and hDP1 receptors respectively). Suppresses PGD2-induced migration of human eosinophils (IC50 = 170 nM).

Product Specifications

Molecular Weight

416.47

Formula

C21H21FN2O4S

Storage

Desiccate at -20°C

Purity

≥98% (HPLC)

Chemical Name

(3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid

CAS Number

116649-85-5

PubChem ID

123879

InChI Key

LDXDSHIEDAPSSA-OAHLLOKOSA-N

SMILES

FC(C=C4)=CC=C4S(N[C@@H](C3)CCC2=C3C1=CC=CC=C1N2CCC(O)=O)(=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 41.65 100
Ethanol 41.65 100

Preparing Stock Solutions for BAY-u 3405

The following data is based on the product molecular weight 416.47

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.40 mL 12.01 mL 24.01 mL
5 mM 0.48 mL 2.40 mL 4.80 mL
10 mM 0.24 mL 1.20 mL 2.40 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

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Product Documents for BAY-u 3405

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for BAY-u 3405

For research use only

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