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BAY-u 3405

Tocris Bioscience a Bio-Techne Brand

Prostanoid Receptor Antagonists Small Molecule
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Key Product Details

Description: Dual TP/DP2 (CRTH2) receptor antagonist
Alternative Names: Ramatroban
Chemical Name: (3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid
Purity: ≥99% (HPLC)
Molecular Weight: 416.47

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  • BAY-u 3405 inhibits 15d-PGJ2-induced p38 activation
    Name: Chintan Koyani
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Cardiomyocytes
    HL-1 cardiomyocytes were pre-incubated with BAY-u 3405 (2 µM, 30 min) followed by treatment with 15d-PGJ2 (15 µM, 30 min) to follow p38 activation using Western blot analysis. BAY-u 3405 completely abolished 15d-PGJ2-induced p38 phosphorylation.
    BAY-u 3405 Serum 2732

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Product Documents for BAY-u 3405

Certificate of Analysis

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