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Bafilomycin A1

Tocris Bioscience a Bio-Techne Brand

H+-ATPase Inhibitors Small Molecule
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1334/100U
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Key Product Details

Description: H+-ATPase (vacuolar) inhibitor
Chemical Name: (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-Hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one
Purity: ≥95% (HPLC)
Molecular Weight: 622.84

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Citations for Bafilomycin A1 (52)

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Customer Reviews for Bafilomycin A1 (3)

4.3 out of 5
3 customer ratings
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  • test
    Name: Xiaogang Wang
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: Human Macrophages
    We used BafA inhibitor to investigate the autophagy induced by bacterial toxins. To confirm whether BafA1 works, human macrophages were treated with or without 100 nM BafA for 1 h, and the levels of LC3-I and LC3-II within human macrophages were determined by western blot using LC3 antibody. As expected (shown in figure), treatment of cells with BafA1 resulted in an increased level of LC3-I and LC3-II, suggesting that the fusion of autophagosomes and lysosomes was blocked and resulted in the accumulation of autophagosomes.
    Bafilomycin A1 Serum 1334
  • BAF
    Name: shubham dubey
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: H9C2
    Treated H9C2 cells to check the autophagy.
    Bafilomycin A1 Serum 1334
  • Good autophagy inhibitor
    Name: JING HE
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: HT29
    HT29 cells transfected with ad-mRFP-GFP-LC3 adenovirus after incubation with or without LPS and Baf A1 at different time points.
    Bafilomycin A1 Serum 1334

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Product Documents for Bafilomycin A1

Certificate of Analysis

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