Autocamtide-2-related inhibitory peptide, myristoylated

Name: Autocamtide-2-related inhibitory peptide, myristoylated
Brand: Tocris Bioscience
SKU: 5959

Tocris Bioscience, part of Bio-Techne | Catalog # 5959

Citations (1)

COA / SDS

CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide

Key Product Details

Description:	CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide
Alternative Names:	Myr-AIP,AIP Myristoylated
Purity:	≥95% (HPLC)
Molecular Weight:	1708.12

View Full Technical Details for Autocamtide-2-related inhibitory peptide, myristoylated

Technical Data
Citations

Biological Activity for Autocamtide-2-related inhibitory peptide, myristoylated

Autocamtide-2-related inhibitory peptide, myristoylated is a CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide (Cat No. 1688). Pretreatment blocks reinstatement of morphine-seeking behavior in vivo.

Technical Data for Autocamtide-2-related inhibitory peptide, myristoylated

M. Wt	1708.12
Formula	C₇₈H₁₄₂N₂₂O₂₀
Single Letter Sequence	KKALRRQEAVDAL (Modifications: Lys-1 = Myr-Lys)
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	201422-04-0
PubChem ID	121513908
InChi Key	QKOOKZWMKXOQRL-YJDHHEDVSA-N
Smiles	[H]N[C@@H](CCCCNC(=O)CCCCCCCCCCCCC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Autocamtide-2-related inhibitory peptide, myristoylated

Solubility

Soluble to 1mg/ml in water

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References for Autocamtide-2-related inhibitory peptide, myristoylated

References are publications that support the biological activity of the product.

Liu Inhibition of CaMKII activity in the nucleus accumbens shell blocks the reinstatement of morphine-seeking behavior in rats. Neurosci.Lett. 2012 PMID: 22579819
Ishida A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem.Biophys.Res.Commun. 1995 PMID: 7626114
Laabich Neuroprotective effect of AIP on N-methyl-D-aspartate-induced cell death in retinal neurons. Brain Res.Mol.Brain Res. 2000 PMID: 11146104